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研究对象为肯尼亚Coast省Kauale区Mvindeni小学的学生,几乎全部感染钩虫(以美洲钩虫为主)及鞭虫,约50％感染蛔虫。于1986年3月进行检查和治疗(Ⅰ.检),同年9月进行随访(Ⅱ检)。在Ⅰ检中,将儿童按性别随机分配入阿苯达唑组(A组)和安慰剂组(PL组)。A组(78例)用单剂400mg阿苯达唑,血红蛋白低于9.0g/dl的患者予以硫酸亚铁6周。PL组(72例)用等量相似的安慰剂,以上均由工作人员看服。粪检用改良的Kato法,取50mg粪便涂片覆以浸泡于甘油孔雀绿溶液的透明纸,30～60分钟后计数钩虫卵,以每克粪虫卵数表示。用Jelliffe法测算儿童生长率,包括体重、身高、上臂中部臂围、三
The study was conducted at Mvindeni Elementary School in Kauale, in the Coast Province of Kenya. Almost all of them were infected with hookworms (mainly hookworms) and whipworms, and about 50% were infected with roundworms. In March 1986 for examination and treatment (Ⅰ. Seized), the same year in September for follow-up (Ⅱ seized). In the I test, children were randomly assigned to albendazole (Group A) and placebo (PL) by sex. Group A (78 patients) received a single dose of 400 mg albendazole and hemoglobin less than 9.0 g / dl for six weeks with ferrous sulfate. PL group (72 patients) with the same amount of placebo, the above are by the staff watching service. Stool test Using a modified Kato method, 50 mg of stool smear was covered with clear paper soaked in glycerol green malachite solution, and hookworm eggs were counted 30 to 60 minutes later to count the number of eggs per gram of stool. Use the Jelliffe method to measure children’s growth rate, including body weight, height, middle arm arm circumference, three