严重哮喘患者气道的持续性炎症可能是支气管高反应性(BHR)的一个重要因素。当前,哮喘患者死亡率仍趋上升,亦可能与治疗较少针对减轻气道炎症和降低 BHR 有关。本文旨在比较联用二丙酸氯地米松(BDP)和舒喘灵(S)、单用 BDP、或用安慰剂对特异性变应原接触期过敏性哮喘患儿的疗效。30例哮喘患儿,男24,女6例,年龄6～14(平均9.6±2.3)岁。其中22例对季节性过敏原、8例对常年性过敏原过敏。对上述患儿分别于春季及秋冬季即患儿最密切接触特异性变应原时期观察1个月。病例按双盲随机法分为3组,每组10例。第1组给予 Persistent inflammation of the airways in severe asthmatics may be an important factor in bronchial hyperresponsiveness (BHR). At present, the mortality rate of asthma patients is still rising, and may also be related to the less treatment to reduce airway inflammation and reduce BHR. This article aims to compare the efficacy of beclomethasone dipropionate (BDP) and salbutamol (S), BDP alone, or placebo for allergic asthma in children exposed to specific allergens. 30 cases of asthmatic children, 24 males and 6 females, aged 6 to 14 (average 9.6 ± 2.3) years old. Of these, 22 were allergic to seasonal allergens and 8 were allergic to perennial allergens. The children were observed in the spring and autumn and winter, respectively, the most close contact with specific allergens during the observation period of 1 month. The patients were divided into 3 groups according to double-blind randomization method, 10 cases in each group. Group 1 is given