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多囊卵巢综合征(PCOS)是生育期妇女最常见的妇科内分泌疾病,可能由某些遗传基因与环境因素的相互作用所致,但其确切病因至今尚未阐明。PCOS患者外周血中性粒细胞、嗜酸粒细胞、单核细胞、淋巴细胞、C反应蛋白、肿瘤坏死因子α、白细胞介素水平升高,提示PCOS可能是一种慢性低度炎症。PCOS免疫发病机制的研究将为PCOS的病因学提供新的理论支撑,为PCOS的治疗提供新的方法。
Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disease in women of reproductive age, which may be caused by the interaction of some genetic and environmental factors, but its exact etiology has not been elucidated so far. PCOS patients with peripheral blood neutrophils, eosinophils, monocytes, lymphocytes, C-reactive protein, tumor necrosis factor alpha, interleukin levels, suggesting that PCOS may be a chronic low-grade inflammation. The study of PCOS immune pathogenesis will provide a new theoretical support for the etiology of PCOS and provide a new method for the treatment of PCOS.