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目的:探讨64排多层螺旋CT(MSCT)冠状动脉成像和心肌肌钙蛋白(cTnI)在急性冠脉综合征的联合应用价值及相互关系。方法:稳定型心绞痛(SA)组为对照组,急性冠脉综合征(ACS)组分为不稳定型心绞痛(UA)组及急性心肌梗死(AMI)组,3组受试患者进行cTnI和64排MSCT冠状动脉成像检查,比较2组cTnI和64排MSCT冠状动脉成像结果。结果:ACS组cTnI均明显高于SA组,2组间cTnI水平差异有统计学意义(P<0.01)。2组冠脉狭窄程度比较差异有统计学意义,即ACS组以轻、中度狭窄为主,SA组以重度狭窄为主。结论:64排MSCT冠状动脉成像联合cTnI检测,对判断冠状动脉狭窄程度、斑块稳定性及心肌受损程度具有较高的敏感性和准确性,对ACS的诊断治疗及预后评价有重要应用价值。
Objective: To investigate the combined application of 64-slice multi-slice spiral CT (MSCT) coronary angiography and cardiac troponin (cTnI) in acute coronary syndromes. Methods: The patients in stable angina pectoris (SA) group served as the control group. The patients with acute coronary syndrome (ACS) were divided into unstable angina pectoris group (UA) and acute myocardial infarction group (AMI) Row MSCT coronary angiography, comparing two groups of cTnI and 64 rows MSCT coronary angiography results. Results: The cTnI in ACS group was significantly higher than that in SA group. There was significant difference in cTnI level between the two groups (P <0.01). There were significant differences in the degree of coronary stenosis between the two groups, namely ACS group with mild to moderate stenosis, SA group mainly with severe stenosis. Conclusion: 64-slice MSCT coronary angiography combined with cTnI detection has high sensitivity and accuracy in judging the degree of coronary artery stenosis, plaque stability and myocardial damage, and has important value in the diagnosis, treatment and prognosis evaluation of ACS .