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用氨氯地平（络活喜）（ＡｍｏｌｏｄｉｐｉｎｅＮｏｒｖａｓｃ）对３１例慢性肾功能不全伴高血压患者进行为期３个月的临床观察，治疗后血尿素氮（ＢＵＮ）、血肌酐（Ｓｃｒ）水平明显下降（１６．１±５．３ｖｓ１３．２±６．２ｍｍｏｌ／Ｌ，Ｐ＜０．０５；２５８±６２ｖｓ２２１±８２ｍｍｏｌ／Ｌ，Ｐ＜０．０５）；收缩压和舒张压明显减低（２２．６±０．９ｖｓ９．３±１．６ｋＰａ，Ｐ＜０．０１；１２．７±０．５ｖｓ１０．６±０．８ｋＰａ，Ｐ＜０．０１），同时对尿蛋白有降低作用（１．４２±０．５ｖｓ１．２３±０．６ｇ／２４ｈ，Ｐ＞０．０５），副作用轻微。认为络活喜可作为治疗慢性肾功能不全伴高血压病人的有效药物之一。
A total of 31 patients with chronic renal failure and hypertension were treated with AmolodipineNorvasc for 3 months. The levels of BUN and Scr were significantly decreased after treatment (Amoxicillin, Amoxicillin) 16.1 ± 5.3 vs 13.2 ± 6.2 mmol / L, P <0.05; 258 ± 62 vs 221 ± 82 mmol / L, P <0.05); systolic and diastolic blood pressures decreased significantly .9 vs9.3 ± 1.6 kPa, P <0.01; 12.7 ± 0.5 vs10.6 ± 0.8 kPa, P <0.01), while reducing urinary protein (1.42 ± 0. 5vs1.23 ± 0.6g / 24h, P> 0.05), minor side effects. It is considered as one of the effective drugs for treating patients with chronic renal insufficiency and hypertension.