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目的回顾性分析风心病患者冠状动脉粥样硬化的患病率,并分析风心病病人、风心病合并冠心病病人、正常人血液中的胆红素,探究其在风心病合并冠心病的发生发展上是否存在一定差异性。方法选择自2004年5月￣2006年9月因风心病进行瓣膜置换术而行冠脉造影的患者126例,分析其冠脉造影的资料,分析风心病病人、风心病合并冠心病病人、正常人的胆红素,计算风心病合并冠心病的发病率,并将此患病率分别与高血压病人、糖尿病病人、高脂血症病人、老年高危人群的冠心病患病率进行统计学上的比较。结果126例风心病患者中合并冠心病10人,患病率7.9%,低于高血压病人、糖尿病病人、高脂血症病人、老年高危人群合并冠心病的患病率,比较有统计学意义。风心病患者血液中胆红素含量高于风心病合并冠心病者,明显高于正常人,比较有统计学意义。结论风心病患者冠心病患病率较低,血液中的胆红素较高可能是保护因素之一。
Objective To retrospectively analyze the prevalence of coronary atherosclerosis in patients with rheumatic heart disease and to analyze the bilirubin in the patients with rheumatic heart disease, rheumatic heart disease and coronary heart disease and normal subjects and to explore the occurrence and development of coronary heart disease in rheumatic heart disease Whether there is a certain difference. Methods From May 2004 to September 2006, 126 patients undergoing coronary angiography due to rheumatic heart disease were enrolled. The data of coronary angiography were analyzed. The patients with rheumatic heart disease, patients with rheumatic heart disease and coronary heart disease were analyzed. Human bilirubin, calculate the incidence of coronary heart disease with rheumatic heart disease and coronary heart disease prevalence rate of hypertensive patients, diabetic patients, patients with hyperlipidemia, elderly at high risk of coronary heart disease were statistically Comparison. Results 126 patients with rheumatic heart disease in 10 patients with coronary heart disease, the prevalence rate of 7.9%, lower than the hypertensive patients, diabetic patients, patients with hyperlipidemia, elderly high-risk groups with coronary heart disease prevalence, more statistically significant . The content of bilirubin in the blood of patients with rheumatic heart disease is higher than that of patients with coronary heart disease of rheumatic heart disease, which is obviously higher than that of normal people, which is statistically significant. Conclusion The prevalence of coronary heart disease in patients with rheumatic heart disease is low, and the higher bilirubin in blood may be one of the protective factors.