IgA肾病于 196 9年由Berger首先描述 ,被公认为当今世界上最常见的原发性肾小球疾病 ,其病理特点是肾小球系膜细胞增生及系膜基质增加 ,并在系膜区和 /或肾小球毛细血管袢出现以IgA为主的免疫球蛋白及补体成分的沉积 ,临床表现为血尿和 /或蛋白尿 ,上呼吸道感染常导致血尿复发 IgA nephropathy was first described by Berger in 1919 and is recognized as the most common primary glomerular disease in the world today. Its pathological features are mesangial cell proliferation and increased mesangial matrix, And / or glomerular capillary 袢 appear IgA-based immunoglobulin and complement deposition, the clinical manifestations of hematuria and / or proteinuria, upper respiratory tract infection often leads to hematuria recurrence