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目的研究曲美他嗪改善扩张型心肌病患者心功能的疗效。方法 60例扩张型心肌病患者随机分为治疗组和对照组各30例,治疗组在常规抗心力衰竭治疗的基础上加用曲美他嗪,对照组给予常规抗心力衰竭治疗。观察治疗前后临床疗效、6min步行试验、超声指标的变化。结果治疗6个月后,治疗组治疗后其疗效、6min步行试验、超声指标均较对照组有明显改善(P<0.05)。结论曲美他嗪能明显改善扩张型心肌病患者的心功能,逆转心室重构。
Objective To study the efficacy of trimetazidine in improving cardiac function in patients with dilated cardiomyopathy. Methods Sixty patients with dilated cardiomyopathy were randomly divided into treatment group (30 cases) and control group (30 cases). The treatment group was given trimetazidine on the basis of routine anti-heart failure treatment, while the control group was given conventional anti-heart failure treatment. Observed before and after treatment of clinical efficacy, 6min walk test, ultrasound changes. Results After 6 months of treatment, the curative effect, 6-minute walk test and ultrasound index of the treatment group were significantly improved compared with the control group (P <0.05). Conclusion Trimetazidine can significantly improve cardiac function in patients with dilated cardiomyopathy and reverse ventricular remodeling.