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目的:探讨和总结改良根治术Ⅰ式治疗乳腺癌的方法和疗效。方法:回顾性分析68例乳腺癌(Ⅰ期28例,Ⅱ期35例,Ⅲ期5例)施行改良根治术Ⅰ式的治疗效果。结果:68例患者中发生皮下积液6例(8.8%),胸肌挛缩伴同侧上臂运动障4例(6.0%),上臂感觉障碍3例(4.4%)。3年生存率86.4%,5年生存率63.9%,其中Ⅰ期为80.2%,Ⅱ期为50.8%,Ⅲ期为37.7%。结论:改良根治术Ⅰ式治疗乳腺癌应注意选择手术的适应证和禁忌证,注重保护胸前神经的内外侧分支和肋间臂神经,注重新辅助化疗的疗效,以提高术后生活质量。
Objective: To explore and summarize the modified radical mastectomy type Ⅰ breast cancer treatment methods and efficacy. Methods: A retrospective analysis of 68 cases of breast cancer (stage Ⅰ 28 cases, stage Ⅱ 35 cases, stage Ⅲ 5 cases) modified radical mastectomy Ⅰ type of treatment. RESULTS: Sixty-eight (8.8%) of the 68 patients developed subcutaneous effusions, with pectoral muscle contracture accompanied by ipsilateral upper arm motor dysfunction in 4 cases (6.0%) and upper arm sensory disturbance in 3 cases (4.4%). The 3-year survival rate was 86.4% and the 5-year survival rate was 63.9%, of which stage Ⅰ was 80.2%, stage Ⅱ was 50.8% and stage Ⅲ was 37.7%. CONCLUSION: Modified radical mastectomy for breast cancer should pay attention to the indications and contraindications of operation, pay attention to the protection of the medial and lateral branches of the thoracic nerve and the intercostobrachial nerve, pay attention to the effect of neoadjuvant chemotherapy to improve postoperative quality of life.