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哮喘是一种常见的呼吸系统疾病。哮喘可分为过敏性哮喘、职业性哮喘、感染性哮喘等多种类型,气道炎症是所有类型哮喘的共同特征。本研究构建哮喘大鼠模型,对比罗红霉素处理后和未处理小鼠肺组织中i NOS表达水平,以期为治疗哮喘提供新思路。1材料与方法1.1材料SD雄性大鼠30只,40日龄,体重90~100g,由海南医学院动物实验中心提供。IL-4酶联免疫检测试剂盒、IFN-γ酶联免疫检测试剂盒(上海酶
Asthma is a common respiratory disease. Asthma can be divided into multiple types of allergic asthma, occupational asthma, infectious asthma, airway inflammation is a common feature of all types of asthma. In this study, asthmatic rat model was established to compare iNOS expression level in the lung tissue of roxithromycin-treated and untreated mice, and to provide new ideas for the treatment of asthma. 1 Materials and Methods 1.1 Materials SD male rats 30, 40 days old, weighing 90 ~ 100g, provided by the Hainan Medical College Animal Experimental Center. IL-4 enzyme-linked immunosorbent assay kit, IFN-γ ELISA kit (Shanghai enzyme