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多项二级预防试验证实,普伐他汀和阿司匹林均可降低心血管疾病的发病危险。普伐他汀主要有延迟抗动脉硬化作用,而阿司匹林具有即时抗血小板效应。为评价两种药物合用能否获得额外临床效益而进行荟萃分析。 方法共荟萃5项普伐他汀(40mg/d)二级
A number of secondary prevention tests confirmed that pravastatin and aspirin can reduce the risk of cardiovascular disease. Pravastatin has mainly delayed anti-atherosclerosis, while aspirin has an immediate anti-platelet effect. A meta-analysis was conducted to evaluate whether additional benefits of the two drugs can be obtained. Methods A total of five combinations of pravastatin (40mg / d) two