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先前的研究表明5型磷酸二酯酶在前列腺血管床的内皮和平滑肌细胞中显著高表达,这一现象可能导致PDE5抑制剂对前列腺的血流产生调控。本研究旨在研究PDE5在人和鼠的包括脉管系统在内的下尿路
Previous studies have shown that phosphodiesterase type 5 is significantly overexpressed in the endothelial and smooth muscle cells of the prostatic vascular bed, a phenomenon that may result in PDE5 inhibitors regulating the prostatic blood flow. The aim of this study was to investigate the lower urinary tract of PDE5 in human and mouse including vasculature