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近年来输精管切除术已成为一种广泛应用的节育措施。不过,根据某些动物实验资料,有人提出输精管切除术可能导致动脉粥样硬化的发病率增加。认为这种动脉壁的损害是由免疫介导的炎性反应造成。作者对输精管切除术前后受术者的血清胆固醇、甘油三酯(TG)及游离脂肪酸进行了研究,旨在进一步明确输精管切除术的远期危险性。 14例年龄28～56岁自愿绝育健康男子,局麻下行常规输精管切除术。禁食12小时上午9时采血。分别于术前6～8周、术后1周、3月、12月测定血清胆固醇、TG及游离脂肪酸水平。结果可见受术者术后一年随访期间未发生并发症,体重无明显改变,术后三个月检查均无精子。血清总胆固醇含量明显下降,但高密度脂蛋白-胆固醇(HDL-C)无改变。平均血清低密度脂蛋
Vasectomy has become a widely used birth control measure in recent years. However, according to some animal experimental data, it was suggested that vasectomy may lead to an increased incidence of atherosclerosis. It is thought that this damage to the arterial wall is caused by an immune-mediated inflammatory reaction. The authors studied the serum cholesterol, triglycerides (TG) and free fatty acids before and after vasectomy to further understand the long-term risk of vasectomy. Fourteen healthy volunteers aged 28-56 years underwent voluntary vasectomy under local anesthesia. Fasting 12 hours at 9 am blood. Serum cholesterol, TG and free fatty acid levels were measured at 6-8 weeks preoperatively, 1 week, 3 months and 12 months after operation. The results showed no complications during one year follow-up after surgery, no significant change in body weight, no sperm after three months of examination. Serum total cholesterol levels decreased significantly, but high-density lipoprotein-cholesterol (HDL-C) unchanged. Mean serum LDL