In general, submerged pipes passing over the sedimentary bed of seas are installed for transmitting oil and gas to coastal regions.The stability of submerged pipes can be threatened with waves and coastal flows occurring at coastal regions. In this study, for the first time, the adaptive neuro-fuzzy inference system (ANFIS) is optimized using the particle swarm optimization (PSO) algo-rithm, and a meta-heuristic artificial intelligence model is developed for simulating the scour pattern around submerged pipes located in sedimentary beds. Afterward, six ANFIS-PSO models are developed by means of parameters affecting the scour depth. Then, the superior model is detected through sensitivity analysis. This model has the function of all input parameters. The calculated correlation coefficient and scatter index for this model are 0.993 and 0.047, respectively. The ratio of the pipe distance from the sedimentary bed to the submerged pipe diameter is introduced as the most effective input parameter. PSO significantly improves the performance of the ANFIS model. Approximately 36％of the scour depths simulated using the ANFIS model have an error less than 5％, whereas the value for ANFIS-PSO is roughly 72％.