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目的:研究蒙脱石散联合止泻保童颗粒对腹泻患儿血清C反应蛋白(CRP)及心肌酶谱水平的影响。方法:回顾性分析2012年7月至2013年6月在本院进行治疗的腹泻患儿,39例采取蒙脱石散治疗(对照组),39例采取蒙脱石散联合止泻保童颗粒治疗(观察组)。比较两组患儿有关症状改善时间和临床疗效,分析两组患儿治疗前后血清CRP及心肌酶谱水平。结果:治疗后,观察组总有效率显著高于对照组(P<0.05),血清CRP、谷丙转氨酶(ALT)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、谷草转氨酶(AST)、肌酸激酶同工酶(CK-MB)水平均显著低于对照组(P<0.05),止泻时间、大便恢复至正常时间、退热时间显著短于对照组(P<0.05)。结论:腹泻患儿经蒙脱石散联合止泻保童颗粒治疗较单用蒙脱石散能更有效降低患儿血清CRP水平,改善患儿的心肌酶谱水平,患儿的临床症状可快速恢复,临床疗效更好。
Objective: To investigate the effects of montmorillonite powder combined with Zhiganbao on serum level of C-reactive protein (CRP) and myocardial enzymes in children with diarrhea. Methods: A retrospective analysis of children with diarrhea treated in our hospital from July 2012 to June 2013, 39 patients treated with montmorillonite (control group) and 39 patients treated with montmorillonite powder Treatment (observation group). The relative improvement of symptoms and clinical efficacy were compared between the two groups. Serum CRP and myocardial enzymes were measured before and after treatment in both groups. Results After treatment, the total effective rate in the observation group was significantly higher than that in the control group (P <0.05). Serum levels of CRP, ALT, LDH, CK, AST ), Creatine kinase (CK-MB) were significantly lower than those in the control group (P <0.05). Antidiarrheal time and stool returned to normal time, and the fever time was significantly shorter than that of the control group (P <0.05). Conclusion: In children with diarrhea treated by montmorillonite combined with anti-diarrhea Bao Tong particles than single montmorillonite powder can effectively reduce the serum CRP levels in children to improve the level of myocardial enzymes in children with clinical symptoms can be quickly Recovery, better clinical efficacy.