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目的探讨老年糖尿病患者血管意外风险与CRP的关系。方法选取糖尿病合并大血管病变患者57例作为A组,不合并大血管病变的糖尿病患者46例作为B组,以及健康体检者42例作为C组,A、B两组空腹血糖水平无明显差异。测定三组总胆固醇、高密度及低密度脂蛋白、24h微量白蛋白尿以及超敏慢反应蛋白含量。结果三组胆固醇、高密度及低密度脂蛋白以及24h微量白蛋白尿无明显差异(P>0.05)。B组患者CRP明显低于C组,A组患者CRP水平明显低于B、C两组,且差异有统计学意义(P<0.05)。结论对老年糖尿病患者CRP水平进行监测,当期>3mg/L时,即给予早期积极治疗,如降糖、降脂、抗栓等,以减少心脑血管意外的发生几率,提高老年人糖尿病患者的生活质量。
Objective To investigate the relationship between vascular accident risk and CRP in elderly diabetic patients. Methods Fifty-seven patients with diabetes mellitus and macroangiopathy were selected as group A, 46 patients with diabetes without macrovascular disease as group B and 42 healthy subjects as group C. There was no significant difference in fasting plasma glucose between groups A and B. Three groups of total cholesterol, high-density and low-density lipoprotein, 24h microalbuminuria and hypersensitive slow-acting protein content were determined. Results The three groups of cholesterol, high density and low density lipoprotein and 24h microalbuminuria had no significant difference (P> 0.05). The CRP in group B was significantly lower than that in group C, and the level of CRP in group A was significantly lower than that in group B and C (P <0.05). Conclusion CRP levels in elderly patients with diabetes mellitus were monitored at the current period of> 3mg / L, ie, early active treatment such as hypoglycemic, lipid-lowering, antithrombotic and so on, in order to reduce the incidence of cardiovascular and cerebrovascular accidents and improve the elderly diabetic patients Quality of Life.