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文章从中药“十八反”临床渊源、临床的不同认识去分析探讨“十八反”问题,从合理用药角度思考其发展思路:中药“十八反”研究是临床药学合理用药的研究范畴,应加强临床安全性研究,在充分证明药物的安全性后,进行相关的有效性研究。全面考虑药材基源、加工方法、配比关系、制剂形式、给药途径、给药剂量等因素,尽量统一规范,以明确其涵盖范围和量效关系,促进其研究结果的不断完善。
The article from the traditional Chinese medicine “eighteen anti” clinical origin, different clinical knowledge to analyze the “eighteen anti” problem, from the perspective of rational use of drugs to consider its development ideas: Chinese medicine “eighteen anti” research is clinical pharmacy Reasonable drug research areas, should enhance clinical safety studies, in the full proof of the safety of drugs, the relevant validity of the study. Comprehensive consideration of the basis of medicinal materials, processing methods, the relationship between the ratio, the preparation of forms, route of administration, dose and other factors, as much as possible unified norms to clarify its coverage and dose-effect relationship and promote the continuous improvement of their research results.