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胚胎毒和动物致畸的因素是多方面的。化学药物也是其中之一,它们与致畸活性之间的关系,于1952年Hamburgh M已在小鼠身上用台盘蓝进行致畸研究。另在鸡、小鼠、大鼠、狗,甚至人体上均有研究。国外文献报道很多。敌枯双农药是一种噻二唑类化合物,对水稻白叶枯病、花生青枯病和柑桔溃疡病有优异的防治效果。国内四川大学生物系敌枯双科研组以及王方元等都有这方面的研究。我们认为深入研究敌枯双的胚胎毒及其致畸效应,以便找出解毒方法,从而更好应用于农业,仍有现实意义。
Embryo poisoning and animal teratogenic factors are many. Chemical drugs are also one of them, and they are related to the teratogenicity. In 1952, Hamburgh M has used terrestrial blue for teratogenesis in mice. It has also been studied in chickens, mice, rats, dogs, and even humans. There are many foreign reports. Antagonistic double pesticide is a thiadiazole compound, which has excellent control effect on rice bacterial blight, peanut bacterial wilt and citrus canker. There are researches in this field in the Biology Research Group and Wang Fangyuan of Biology Department of Sichuan University. We believe that the in-depth study of the embryotoxic and teratogenic effects of the enemy and the Bacteria, in order to find a detoxification method, so as to be better applied to agriculture, is still of practical significance.