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近日,中国农业科学院哈尔滨兽医研究所研究员郑永辉带领的基础免疫创新团队发现,内质网Ⅰ型α-甘露糖苷酶能够诱导艾滋病病毒囊膜糖蛋白降解,继而抑制艾滋病病毒的复制,最终有望达到治疗的目的。研究成果近期发表于《生物化学杂志》。由于艾滋病病毒感染人体后会在细胞内形成一个潜伏病毒库,在中断治疗后能迅速释放病毒,
Recently, the basic immunological innovation team led by Zheng Yonghui, a researcher at Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, found that the endoplasmic reticulum type Ⅰ α-mannosidase can induce the degradation of HIV glycoprotein glycoproteins, and then inhibit the replication of HIV, which is finally expected to reach treatment the goal of. The research results recently published in the Journal of Biochemistry. As HIV infection in the human body after the formation of a latent virus in the library, in the interruption of treatment can quickly release the virus,