Molecular biology of heart disease

来源 :World Journal of Cardiology | 被引量 : 0次 | 上传用户:DownLoad0006
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Dr. Robert Roberts is currently Professor of Medicine and Director of the Ruddy Canadian Cardiovascular Genetics Centre along with being President and CEO of the University of Ottawa Heart Institute. Prior to this appointment, he was Chief of Cardiology for 23 years at Baylor College of Medicine, Houston, Texas. His original research was in cardiac enzymology which led to the development of the MBCK test which was the standard diagnostic assay for myocardial infarction for more than 3 decades. In the late 1970s, his research interests switched to molecular biology and the genet- ics of cardiomyopathies. He is regarded as one of the founders of molecular cardiology and has identified and sequenced more than 20 genes responsible for cardiovascular disorders. In the past 6 years, he has pursued genome-wide association studies to identify genes predisposing to coronary artery disease (CAD) and myocardial infarction. The first genetic variant for CAD, 9p21, was identified by Dr. Robert’s laboratory and, in collaboration with the international consortium, CARDIoGRAM, has identified 13 novel genes for CAD. Dr. Robert Roberts is currently Professor of Medicine and Director of the Ruddy Canadian Cardiovascular Genetics Center along with being President and CEO of the University of Ottawa Heart Institute. Prior to this appointment, he was Chief of Cardiology for 23 years at Baylor College of Medicine His original research was in cardiac enzymology which led to the development of the MBCK test which was the standard diagnostic assay for myocardial infarction for more than 3 decades. In the late 1970s, his research interests switched to molecular biology and the genet- ics of cardiomyopathies. He is pursued as one of the founders of molecular cardiology and has identified and sequenced more than 20 genes responsible for cardiovascular disorders. In the past 6 years, he has pursued genome-wide association studies to identify genes predisposing to coronary artery disease (CAD) and myocardial infarction. The first genetic variant for CAD, 9p21, was identified by Dr. Robert’s laboratory and, in collaboration with the international consortium, CARDIoGRAM, has 13 identified novel genes for CAD.
其他文献
离子软氮化能大幅度提高钢铁零件的疲劳强度、耐磨性及抗咬合能力,而且处理时间短、变形小、适用钢种范围广。但硬度较低,硬化层深度较浅,对重负荷零件不适宜。为了充分发挥
本文根据近十年来我国地声观测的某些结果,分析了地声的时-空分布特点,并估计了透入基岩面上和水面中的声压.同时与震前动物异常特点,以及与人和某些动物的听觉和振动感受器
大范甘迪的下课固然有些“替罪羊”的味道,但如果对莱利和大范甘迪的渊源熟悉的人都很清楚:莱利的重新上台是他和大范甘迪之间很默契的权杖交接,并没有外界想象的那么复杂。
在中国与世界的交流愈来愈频繁的今天,英语教学变得格外重要,而中国的传统教学方法及其效果却不尽人意,这使借鉴国外先进教学思想和方法的问题显得更加迫切。《牛津英语教师
凌特公司(Linear)近日推出用于单电源应用的最快速3路视频放大器LT6557。该器件具有延至0.8V电源轨的宽输出摆幅,这使其成为惟一能在采用5V单电源工作时提供全视频摆幅的宽带
上海杨浦区委督查室紧紧围绕重点工作,加快完善督查工作机制,创新督查方式方法,在推动杨浦“三区一基地”建设方面收到良好成效。当前,上海杨浦区正在推进“三区一基地”建设
随着大学英语 CET测试的不断深入和发展 ,测试模式已发生了一些变化 ,针对这些变化 ,学生应改变学习策略 ,适应新的测试趋势。 With the deepening and development of the
近年来,西南边疆地区的边政问题逐渐受到越来越多的关注。由罗彩娟、徐杰舜、罗树杰著的《中国西南边疆治理模式研究》着眼于历史上历代王朝治理西南边疆的不同思想与治策,从
英语和汉语在语态上都有主动和被动之分,但汉语被动语态的应用范围远不如英语宽广。在不少情况下,同一意思、同一句话,英语里习惯用被动语态表达的,汉语里却往往用主动语态:“Heis
黄海是我国四大海域之一,地理上俗分为北黄海和南黄海两部分.其中南黄海以我国胶东半岛东端的成山头至朝鲜白翎岛连线与北黄海分野,南则以长江口至济州岛一线与东海为界;它