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众所周知,糖尿病易致动脉硬化与胰岛素不足有关。但近年则提出,胰岛素能促发动脉硬化,但尚未最后证明。为此,本文对糖尿病患者从年龄、性别、肥胖程度、血压、动脉硬化指标及胰岛素水平诸方面进行研究。研究对象系胰岛素非依赖性糖尿病114例(男76例,女38例),年龄40～70岁(平均55±6岁),病程平均10.7±7.8年,肥胖程度平均108.9±14.7%。114例患者中饮食治疗40例,口服降糖药治疗67例,胰岛素治疗7例。动脉硬化指标:①眼底检查是Keith-W-agener 变化(K—W);②Scheie 动脉硬化(S—S);③放射线检查胸主动脉及腹主动脉钙化;④心电图显示冠状动脉硬化表现。胰岛素水平指标:空腹胰岛素水平(FIRI),100克葡萄糖耐量后2小时血胰岛素水平总和(∑IRI),∑IRI 与葡萄糖耐量试验血糖总和(∑BG)之比(∑IRI/∑BG)及葡萄糖耐量后30分钟血胰岛素增
As we all know, diabetes-induced arteriosclerosis and insulin deficiency related. However, in recent years, it was suggested that insulin can promote atherosclerosis, but it has not yet been proved. To this end, this article in diabetic patients from age, gender, degree of obesity, blood pressure, arteriosclerosis and insulin levels in various aspects of research. The subjects were 114 cases of insulin-independent diabetes mellitus (76 males and 38 females), aged 40-70 years (average 55 ± 6 years) with an average duration of 10.7 ± 7.8 years and an average of 108.9 ± 14.7% of obesity. Forty patients were diet-treated in 114 patients, 67 were treated with oral hypoglycemic agents, and 7 were treated with insulin. Atherosclerosis indicators: ① fundus examination is Keith-W-agener change (K-W); ② Scheie arteriosclerosis (S-S); ③ radiation examination of the thoracic and abdominal aortic calcification; ④ ECG showed coronary atherosclerosis. Insulin level indicators: fasting insulin level (FIRI), the sum of blood insulin levels (ΣIRI) at 2 hours after 100 g of glucose tolerance, the ratio of ΣIRI to total glucose in glucose tolerance test (ΣIRI / ΣBG), and glucose Thirty minutes after the endurance increased blood insulin