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淋巴样间质性肺炎(LIP)组织学改变是以小淋巴细胞和浆细胞为主在肺泡隔和沿淋巴管弥漫性浸润为特征,可原发或伴发于其他疾病,如干燥综合征,重症肌无力和慢性活动性肝炎等。最近在几组AIDS高危人群中观察到以全身淋巴结病为特征的一种综合征,因此又称AIDS相关症候群,组织学表现为滤泡增生。此外,还有多克隆高免疫球蛋白血症、T_4淋巴细胞低下、T_4/T_8淋巴细胞比值倒置等。本文作者报告3例LIP患者,都具有AIDS相关症候群的特征,作者认为LIP是AIDS相关症候群的肺部表现。3例病人均出生于中非的贝宁、刚果和海地(AIDS地方病所在地),2男1女。2例否认同性恋和
Histological changes in lymphoid interstitial pneumonia (LIP) are mainly characterized by small lymphocytes and plasma cells in the diffuse infiltration of the alveolar septa and along the lymphatic vessels, which can be primary or associated with other diseases such as Sjogren’s syndrome, Myasthenia gravis and chronic active hepatitis. A syndrome characterized by generalized lymphadenopathy has recently been observed in several groups of high-risk AIDS patients and is therefore also referred to as AIDS-related syndromes with histological findings of follicular hyperplasia. In addition, there are polyclonal hyperimmunoglobulinism, T 4 lymphocyte low, T 4 / T 8 lymphocyte ratio inversion and so on. The authors report that all 3 LIP patients had characteristics of AIDS-related syndromes. The authors concluded that LIP is a lung manifestation of AIDS-related syndromes. Three patients were born in Benin, Central African Republic, Congo and Haiti (AIDS endemic) and 2 males and 1 female. 2 cases denied homosexuality and