作者对18例原发性高血压病人进行研究,非侵入性地评价异搏停的治疗效果及大剂量单用对左室做功的影响。患法:就诊于高血压诊所至少12个月的5例男性、13例女性原发性高血压病人(年龄31～76岁,平均53.6岁)参加了本研究。充血性心力衰竭和心脏阻滞患者除外。开始研究前十天停用一切抗高血压药物,噻嗪类利尿剂除外。后者剂量不动。空腹8小时,在检查室休息10分钟后,测卧位血压,做超声心动图和心音机械图。然后,每个病人服异搏停240毫克。3小时后,再测血压,重复 The authors studied 18 patients with essential hypertension, non-invasive evaluation of the treatment of verapamil and high-dose single effect on left ventricular work. PATIENTS: Five men and 13 women with essential hypertension (ages 31-76 years, mean 53.6 years) attending hypertensive clinics for at least 12 months participated in this study. Patients with congestive heart failure and heart block except. All antihypertensive drugs were discontinued 10 days before starting the study except for thiazide diuretics. The latter dose does not move. Fasting 8 hours, 10 minutes after the rest in the examination room, blood pressure test lying, do echocardiography and mechanical heart sound machine. Then, each patient was given 240 mg of verapamil. After 3 hours, measure the blood pressure and repeat