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目的对81例反复呼吸道感染(RRI)患儿的免疫功能进行总结分析,研究RRI患儿的免疫功能。方法以81例RRI患儿为研究对象,检测CD3+、CD4+、CD8+,计算CD4+/CD8+比值;测定IgA、IgG、IgM;并与72例正常健康儿童进行比较。结果 RRI患儿的CD3+、CD4+/CD8+比值明显降低,CD8+明显升高,差异有统计学意义(P<0.05);血清IgM、IgG显著高于健康儿童,补体C3明显降低,差异有统计学意义(P<0.05),IgA无显性变化。结论患儿RRI与免疫功能紊乱有关。
Objective To summarize the immune function of 81 children with recurrent respiratory tract infection (RRI) and to study the immune function of children with RRI. Methods Totally 81 children with RRI were enrolled in this study. The ratio of CD3 +, CD4 + and CD8 + was measured and the ratio of CD4 + / CD8 + was calculated. IgA, IgG and IgM were measured and compared with 72 normal healthy children. Results The ratio of CD3 + and CD4 + / CD8 + in patients with RRI was significantly lower than that in healthy children (P <0.05), and the level of CD8 + was significantly higher than that in healthy children (P <0.05) (P <0.05), IgA no significant change. Conclusion RRI in children with immune dysfunction.