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目的探讨胸膜纤维板剥脱术治疗慢性脓胸患者的临床疗效及心肺功能的影响。方法选择2011年6月至2015年12月慢性脓胸患者40例为研究对象,所有患者均进行脓胸病灶清除术+纤维板剥脱术,评价术后第3个月的临床疗效及手术对心肺功能指标[第1 s用力呼气容量(FEV1)、用力肺活量(FVC)、第1 s用力呼气量占用力肺活量的比值(FEV1/FVC)、残气量占预计值的比(RV%pred)、每博输出量(SV)及射血分数(EF)]的影响。结果术后3个月的临床有效率达77.5%,患者的肺功能指标(FEV1、FVC、FEV1/FVC、RV%pred)较术前均明显改善,且与术前比较差异有统计学意义(P<0.0001),心功能指标(SV、EF)与术前比较差异未见统计学意义(P>0.05)。结论对于无明显肺实质破坏的慢性脓胸患者患者,胸膜纤维板剥脱术可明显改善其肺功能,临床疗效显著。
Objective To investigate the clinical efficacy and the effects of cardiopulmonary function in patients with chronic empyema treated with pleural fibreboard stripping. Methods Forty patients with chronic empyema from June 2011 to December 2015 were enrolled in this study. All patients underwent empyema debridement and fibrillation, evaluated the clinical efficacy at 3 months and the effect of surgery on cardiorespiratory function Indicators [FEV1, FVC, FEV1 / FVC, RV% pred, FEV1, FEV1, Per-Bo Output (SV) and Ejection Fraction (EF)]. Results The clinical effective rate was 77.5% at 3 months after operation. The pulmonary function indexes (FEV1, FVC, FEV1 / FVC, RV% pred) in patients were significantly improved compared with that before operation, and there was significant difference compared with preoperative P <0.0001). There was no significant difference between the indexes of cardiac function (SV, EF) and those before operation (P> 0.05). Conclusion In patients with chronic empyema without obvious pulmonary parenchymal damage, pleural fibrillation stripping can significantly improve the lung function, and the clinical curative effect is significant.