日本东洋曹达工业公司研制成功采用光音响检测器的高灵敏度高速液相色谱仪,它可把尿液和血清中所含的微量成分及合成出来的各种化合物,进行分离和检测,所以是医学、生物化学等领域必不可缺的微量分析仪。高速液相色谱仪的灵敏度取决于物质的检测方法,常用的检测方法有:差示折射率法,光吸收法,萤光法等,这些检测方法存在的缺点是:许多检测性能好的物质,灵敏度却差;而一些灵敏度高的物质,检测却受限止。本文介绍的高速液相色谱仪,首次把光音响效果应用于检测方法上,使流动状态的试料液体周期性地 Japan’s Toyo industrial company developed a successful use of high-sensitivity optical detector high-speed liquid chromatography, which can trace the urine and serum contained in the composition and the synthesis of a variety of compounds for separation and testing, it is Medicine, biochemistry and other essential micro-analyzer. Sensitivity of high-speed liquid chromatography depends on the detection of substances, commonly used detection methods are: differential refractive index, light absorption, fluorescence and so on, these detection methods have disadvantages are: many detection of good material, Sensitivity is poor; and some high sensitivity substances, detection is limited. This article describes the high-speed liquid chromatography, for the first time the light and sound effects applied to the detection method, the flow of the sample liquid periodically