已证明克山病病区分布于我国低硒地带，病区居民，特别是主食当地粮食的农业人群恒定地处于低硒状态，补硒可预防急型和亚急型克山病发病。为了进一步探讨硒缺乏在克山病病因和发病中的作用，开展了以下研究：①克山病发病与硒状态改变的观察；②补硒对潜在型克山病患者活检心? It has been proved that Keshan disease is distributed in the low selenium zone of our country. The residents of the ward, especially the agricultural population of the local staple foods, are constantly in a low selenium state. Selenium supplementation can prevent the onset of acute and subacute Keshan disease. In order to further explore the role of selenium deficiency in the etiology and pathogenesis of Keshan disease, the following studies were carried out: (1) The observation of the changes of Keshan disease and selenium status; (2)