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据报告,给正常妇女促性腺激素释放激素(GnRH)后血LH与FSH显著增加,提示无排卵妇女可应用GnRH诱发排卵.但也有人报导了互相矛盾的结果,似乎与GnRH给药的次数有关.本工作目的(1)明确是否需要一个以上的GnRH剂量才能使LH与FSH的释放足以刺激卵巢E_2分泌;(2)评价给予GnRH后高催乳素血症对卵巢E_2分泌的影响.方法:8例18-34岁的正常妇女作为对照,26例继发闭经至少一年以上的患者被分为三组:(1)肌注孕嗣后有撤退性出血(8人,18-32岁),诊
It has been reported that blood LH and FSH are significantly increased after administration of GnRH to normal women, suggesting that ovulation may be induced by GnRH in anovulatory women. However, conflicting results have also been reported which appear to be related to the number of GnRH dosing (1) To determine if more than one GnRH dose is needed to release LH and FSH enough to stimulate ovarian E2 secretion; (2) to evaluate the effect of hyperprolactinemia on E_2 secretion after GnRH administration.Methods: 8 Cases of normal women aged 18-34 as a control, 26 cases of secondary amenorrhea for at least one year or more patients were divided into three groups: (1) muscular injection followed by withdrawal bleeding (8, 18-32 years old), the diagnosis