资料表明,血管内皮细胞能以旁分泌的形式产生许多血管活性物质,并作用于平滑肌细胞而调节血管的收缩。血管内皮细胞能以L-精氨酸为原料合成硝基氧化物,对维持正常的血管紧张性起关键作用。应用精氨酸的类似物——L-硝基精氨酸甲基酯 Data show that vascular endothelial cells in the form of paracrine produce many vasoactive substances, and the role of smooth muscle cells and regulate vascular contraction. Vascular endothelial cells can synthesize nitroxides from L-arginine, which plays a key role in maintaining normal vascular tone. The arginine analogue L-nitroarginine methyl ester is used