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目的：探讨补肾活血中药对慢性肾功能衰竭的治疗效果。方法：将４０例慢性肾功能衰竭患者随机分为保元强肾Ⅱ号组及肾安加开搏通组治疗，观察其对血浆及尿ＳＯＤ、ＭＤＡ及肾功能影响。结果：两组治前均有血浆ＳＯＤ降低及ＭＤＡ增高（Ｐ＜０．０１），尿ＳＯＤ及ＭＤＡ均呈现增高（Ｐ＜０．０１），治疗组治后血浆ＳＯＤ增高、ＭＤＡ降低，尿ＳＯＤ及ＭＤＡ均降低（Ｐ均＜０．０１），ＢＵＮ、ＳＣｒ及ＣＣｒ显著改善（Ｐ＜０．０１）。结论：保元强肾Ⅱ号片有增强抗氧化能力，抑制脂质过氧化作用，从而改善肾功能。
Objective: To investigate the therapeutic effect of Bushen Huoxue Chinese medicine on chronic renal failure. Methods: Forty patients with chronic renal failure were randomly divided into two groups: Baoyuanqiangshen Ⅱ and Shengan Caibutong, and their effects on plasma and urinary SOD, MDA and renal function were observed. Results: Plasma SOD and MDA increased (P <0.01), urinary SOD and MDA increased (P <0.01), plasma SOD increased, MDA decreased, urine SOD And MDA decreased (P <0.01), BUN, SCr and CCr significantly improved (P <0.01). Conclusion: Baoyuqiangshen Ⅱ tablets can enhance the anti-oxidative capacity, inhibit lipid peroxidation, and improve renal function.