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研究活动期溃疡性结肠炎 (UC)的内镜特点 ,以及与主要临床表现的关系。方法 :采用改进的Baron关于UC内镜下活动分级标准对 70例UC患者进行分析 ,并采用Spearman等级相关分析其与主要临床表现的关系。结果 :本组病例中 ,活动度为Ⅰ级占 15 .7% ,Ⅱ级占 2 4.3% ,Ⅲ级占 12 .9% ,Ⅳ级占 47.1%。病变范围 :直肠占 12 .9% ,直肠乙状结肠占 34.3 % ,左半结肠占 2 2 .9% ,右半结肠占 2 .8% ,区域型占 2 .8% ,全结肠占 2 4.3 % ,发生左侧远端结肠者占 70 %。合并息肉为 2 2 .9% ,不典型增生为 7.1% ,直肠上段缩窄为 1.3% ,淋巴瘤为 1.3 %。结肠镜下活动度分级与临床活动指数AI(r=0 .37,P <0 .0 1) ,ESR(r=0 .2 7,P <0 .0 5 ) ,粘液血便的程度 (r=0 .32 ,P <0 .0 1)及次数 (r =0 .2 5 ,P <0 .0 5 )有一定的关联 ,与血红蛋白 (r =- 0 .2 1,P >0 .0 5 ) ,血浆白蛋白 (r =- 0 .2 3 ,P >0 .0 5 )无显著关系。结论 :活动期UC的内镜特点 :活动度以Ⅳ级和Ⅱ级为主 ,病变范围以左侧远端结肠直肠为主 ,息肉发生率为 2 2 .9% ,不典型增生为 7.1% ,内镜下UC的活动度与AI、ESR、粘液血便的程度及次数有一定的关联。
To study the endoscopic features of active ulcerative colitis (UC) and its relationship with the major clinical manifestations. Methods: Seventy patients with UC underwent modified Baron ’s criteria of activity classification of UC endoscopy. Spearman rank correlation analysis was used to analyze the relationship between them and the main clinical manifestations. Results: In this group of patients, the activity of grade Ⅰ was 15.7%, Ⅱ grade was 22.3%, Ⅲ grade was 12.9%, Ⅳ grade was 47.1%. Lesions range: rectal accounted for 12.9%, rectal sigmoid colon accounted for 34.3%, left half colon accounted for 22.9%, right half colon accounted for 2.8%, regional type accounted for 2.8%, total colon accounted for 23.3% Left distal colon occurred in 70%. Concomitant polyps were 22.9%, dysplasia was 7.1%, upper rectum narrowed to 1.3%, and lymphoma was 1.3%. The degree of colon cancer activity classification and clinical activity index AI (r = 0.37, P <0.01), ESR (r = 0.27, P <0.05) 0. 32, P <0. 01) and the number of times (r = 0.25, P <0.05) were correlated with hemoglobin (r = -0.21, P> 0.05) ), Plasma albumin (r = - 0.23, P> 0.05). CONCLUSION: The endoscopic features of active UC are mainly grade IV and grade II. The extent of the lesion is dominated by the left distal colorectum. The incidence of polyps is 22.9% and that of atypical hyperplasia is 7.1% The activity of endoscopic UC and AI, ESR, mucus and bloody stool degree and the number of a certain relationship.