论文部分内容阅读
目的:探讨多形性黄色星形细胞瘤(PXA)的临床、病理和治疗效果。方法:回顾分析21例PXA资料。结果:本组肿瘤占神经上皮肿瘤的0.92％,平均年龄27.0岁。临床表现以癫癎和头痛为主,CT、MRI示81.0％的肿瘤位于大脑浅面,66.7％的肿瘤有囊变。病理上肿瘤细胞呈多形性为主,免疫组化CFAP均阳性。术后14例随访4～39个月,全切加放疗复发率12.5％。结论PXA为罕见的胶质瘤类型,好发于青年,肿瘤全切者预后较好,辅以放疗可减少术后复发率。
Objective: To investigate the clinical, pathological and therapeutic effects of pleomorphic yellow astrocytoma (PXA). Methods: A retrospective analysis of 21 cases of PXA data. Results: This group of tumors accounted for 0.92% of neuroepithelial tumors, with an average age of 27.0 years. Clinical manifestations mainly epilepsy and headache, CT, MRI showed that 81.0% of the tumors located in the superficial surface of the brain, 66.7% of the tumors have cystic degeneration. Pathological tumor cells were pleomorphic, immunohistochemical CFAP were positive. Fourteen patients were followed up for 4 to 39 months, and the total recurrence rate was 12.5%. Conclusion PXA is a rare type of glioma, which occurs in young patients. The patients with complete resection of the tumor have a good prognosis. Combined with radiotherapy, PXA can reduce the recurrence rate.