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目的探讨儿童川崎病(KD)的临床特征、实验室检查及治疗方法 ,提高诊治水平。方法对56例川崎病患儿的病历资料进行回顾性分析和总结。结果典型川崎病可按诊断标准,不典型的川崎病可依据其他特殊表现进行相应的诊断;全部患儿均用阿司匹林常规治疗,其中加用丙种球蛋白40例,加用肾上腺皮质激素14例;治愈40例,好转14例,转院2例,无1例死亡。随访36例,随访时间1～5年,28例患儿<1年恢复正常,2例好转仍在随访观察中。结论大多数川崎病患儿症状较典型,可明确诊断,对于不典型病例也可以根据其他表现作出判断;以大剂量丙种球蛋白治疗川崎病有显著疗效,能有效的防治冠状动脉损害,丙种球蛋白治疗无反应患者应用肾上腺皮质激素治疗效果肯定。
Objective To investigate the clinical features, laboratory tests and treatment of children with Kawasaki disease (KD) and to improve the diagnosis and treatment. Methods 56 cases of Kawasaki disease in children’s medical records were retrospectively analyzed and summarized. Results Kawasaki disease can be diagnosed according to the diagnostic criteria, and atypical Kawasaki disease can be diagnosed based on other special manifestations. All children were treated with aspirin routinely. 40 cases were given gamma globulin and 14 cases were treated with adrenocorticotropic hormone. 40 cases were cured, 14 cases improved, 2 cases transferred to hospital, none of them died. Follow-up 36 cases, follow-up time of 1 to 5 years, 28 cases of children <1 years returned to normal, 2 cases of improvement are still under follow-up observation. Conclusion Most children with Kawasaki disease symptoms are more typical, can be diagnosed, for atypical cases can also be judged based on other performance; high dose of gamma globulin treatment of Kawasaki disease has a significant effect, can effectively prevent coronary artery lesions, gamma ball No response to protein therapy in patients with adrenal cortex hormone treatment effect is affirmed.