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目的研究前列地尔联合腺苷钴胺治疗糖尿病周围神经病变的疗效。方法选择82例2型糖尿病伴有周围神经病变的患者,随机分成两组。在常规应用口服降糖药或胰岛素治疗的基础上,治疗组予以前列地尔10μg+10ml生理盐水,静脉注射,1次/d;腺苷钴胺1.5mg,肌肉注射,1次/d。对照组应用维生素B12500μg,1次/d,肌肉注射。疗程均为3周。结论前列地尔联合腺苷钴胺治疗2型糖尿病周围神经病变取得良好疗效。
Objective To investigate the efficacy of alprostadil combined with adenosine dipicillin in the treatment of diabetic peripheral neuropathy. Methods 82 patients with type 2 diabetes with peripheral neuropathy were selected and randomly divided into two groups. On the basis of routine oral hypoglycemic agents or insulin therapy, the treatment group was treated with alprostadil 10μg + 10ml normal saline, intravenous injection, once a day, adenosylcobalamin 1.5mg, intramuscular injection once a day. The control group with vitamin B12500μg, 1 time / d, intramuscular injection. The course of treatment is 3 weeks. Conclusions Alprostadil combined with adenosylcobalamin treatment of type 2 diabetic peripheral neuropathy achieved good results.