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1960年法国Delay首先报道了一例神经阻断剂致恶性症状群(Neuroleptic Malignant Syndrome,简称NMS),此后各国也先后作了零星报道,1977年国内亦有所报告。现将我们所收集的4例报告如下,并略加讨论。病例报告 (例1)殷某,男,43岁,院号11-42919,1975年5月2日首次住院,诊断反应性精神病。既往有肺结核、类风湿关节炎及肺炎史。无精神病家族遗传史。入院体检及神经系统检查(包括脑电图)阴性,轻度贫血,血压110/80。服氯丙嗪200mg/日,递增至400mg/日。住院第30天,出现流涎增多,四肢不
In 1960 France Delay first reported a case of neuroleptic malignant symptoms (Neuroleptic Malignant Syndrome, referred to as NMS), then countries have also made sporadic reports, in 1977 also reported. Now we collect the 4 cases reported below, and a little discussion. Case Report (Example 1) Yin, male, 43 years old, Hospital No. 11 - 42919, was first hospitalized on May 2, 1975 to diagnose reactive psychosis. Past history of tuberculosis, rheumatoid arthritis and pneumonia. No psychiatric family history. Admission physical examination and neurological examination (including EEG) negative, mild anemia, blood pressure 110/80. Serve with chlorpromazine 200mg / day, increasing to 400mg / day. On the 30th day of hospitalization, drooling increased and limbs did not