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弥散性血管内凝血(DIC)是多种致病因素引起的综合征。特征是循环血液中凝血酶增加,血液处于高凝状态,引起微循环内广泛的血栓形成,因而消耗了大量的凝血因子及血小板,使血液转而处于低凝状态;同时,由于继发性纤维蛋白溶解产物的抗凝作用,引起凝血功能障碍性出血,继而发生器官功能障碍和组织坏死等变化。一般认为孕妇血液具有如下特点:(1)血液凝固性亢进;(2)纤维蛋白溶解系统呈抑制状态;(3)高血脂状态。加以胎盘、蜕膜、羊水等产科促凝物质增加,都使孕妇易于发生 DIC。
Disseminated intravascular coagulation (DIC) is a syndrome caused by a variety of causative factors. Characterized by increased circulating blood thrombin, the blood in a hypercoagulable state, causing a wide range of thrombosis within the microcirculation, which consumes a large number of coagulation factors and platelets, the blood turned to a low coagulation state; the same time, as the secondary fiber Anticoagulant effects of protein lysates, causing coagulation disorders bleeding, followed by organ dysfunction and tissue necrosis and other changes. Generally believed that pregnant women have the following characteristics of blood: (1) blood coagulation hyperthyroidism; (2) fibrinolytic system was inhibited; (3) hyperlipemia. To the placenta, decidua, amniotic fluid and other obstetric procoagulant substances increased, are prone to pregnant women DIC.