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应用流式细胞仪单克隆抗体检测96例女性盆腔肿块患者的外周血T淋巴细胞亚群的分布。结果表明,卵巢良性肿瘤和子宫肌瘤与正常对照组无明显差别,T亚群分布在正常范围内。卵巢癌T4淋巴细胞亚群下降(P<0.01),T8亚群明显上升(P<0.001),T4/T8值下降(P<0.001)。提示卵巢良、恶性肿瘤之间T亚群分布差异有显著性,检测T淋巴细胞亚群对卵巢良、恶性肿瘤的鉴别诊断和早期诊断具有一定的价值。
The distribution of T lymphocyte subsets in peripheral blood of 96 patients with pelvic mass was detected by flow cytometry monoclonal antibody. The results showed that benign ovarian tumors and uterine fibroids and normal control group no significant difference, T subpopulation distribution within the normal range. The T4 lymphocyte subsets decreased (P <0.01), the T8 subpopulation significantly increased (P <0.001), and the T4 / T8 decreased (P <0.001). Prompted ovarian benign and malignant tumor T subgroup distribution between the significant differences, detection of T lymphocyte subsets of benign and malignant ovarian tumors differential diagnosis and early diagnosis has some value.