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目的:探讨多排螺旋CT(128排)低剂量扫描参数下检查孤立性肺内结节的可行性研究。方法:随机连续搜集我院低剂量(30m A)CT肺体检者,发现肺内结节病灶患者13例,对其进一步以常规剂量(350m A)CT精细扫描,比较低剂量扫描及常规剂量扫描肺结节大小差异。结果:两种剂量扫描策略均检查出46枚结节。常规剂量与低剂量测得各部位结节体积分别为:肺尖部:(431.3±92.8)mm~3,(658.4±94.4)mm~3,肺中部:(3025.8±526.7)mm~3,(2989.4±520.4)mm~3,肺底部:(1241.5±438.9)mm~3,(1266.0±447.6)mm~3,肺尖部肺结节大小差异明显,肺中部及肺底部肺结节大小均无显著性差异(P>0.05)。常规剂量与低剂量测得结节体积(除外肺尖部位结节5枚)分别为,组1:(39.8±14.6)mm~3,(40.7±15.5)mm~3;组2:(202±106.3)mm~3,(204.1±103.6)mm~3;组3:(4179.7±4410.4)mm~3,(4190.5±4487.2)mm~3。三组组内测量结果均无显著性差异(P>0.05)。常规剂量与低剂量测得非实性结节密度[(-68.3±24.2)HU,(-64.6±22.8)HU]及实性结节结节密度[(97.5±69.5)HU,(107.2±90)HU]均无统计学差异(P>0.05)。结论:低剂量更加有利于肺内孤立结节患者扫描复查病灶,可以应用推广。
Objective: To investigate the feasibility of examining solitary pulmonary nodules under multi-slice spiral CT (128 rows) low-dose scanning parameters. Methods: A total of 13 lung cancer patients with low-dose (30 m A) CT were randomly and randomly collected. Thirteen patients with pulmonary nodules were randomly divided into three groups. The patients were further scanned with normal dose (350 m A) CT, compared with low-dose and conventional dose Pulmonary nodule size difference. Results: 46 nodules were detected in both dose scanning strategies. The volume of nodules of each part measured in the conventional and low dose groups were as follows: apex of the lung: (431.3 ± 92.8) mm ~ 3, (658.4 ± 94.4) mm ~ 3, middle part of the lung: (3025.8 ± 526.7) mm ~ 2989.4 ± 520.4) mm ~ 3, pulmonary bottom: (1241.5 ± 438.9) mm ~ 3, (1266.0 ± 447.6) mm ~ 3, pulmonary nodule size was significantly different, Significant difference (P> 0.05). The volume of nodules (excluding 5 nodules at the apex of the lung) measured at conventional and low doses were (39.8 ± 14.6) mm ~ 3, (40.7 ± 15.5) mm ~ 3, and group 2: 106.3) mm ~ 3, (204.1 ± 103.6) mm ~ 3; Group 3: (4179.7 ± 4410.4) mm ~ 3, (4190.5 ± 4487.2) mm ~ 3. There was no significant difference between the three groups (P> 0.05). Non-solid nodule density [(-68.3 ± 24.2) HU, (-64.6 ± 22.8) HU] and solid nodular nodule density [(97.5 ± 69.5) HU, (107.2 ± 90 ) HU] had no statistical difference (P> 0.05). Conclusion: Low dose is more conducive to reconstructing solitary pulmonary nodules in patients with recurrent lesions.