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类固醇激素特别是腎上腺皮貭激素在临床上应用范围之广,治疗疾病种类之多,实可与磺胺类药物或抗菌素比拟。但这类激素长期应用时,常产生严重的副作用,使其临床应用受到一定限制。因此,寻找效力強而副作用少的新类固醇激素,具有重大的实际和理論意义。由于各国研究者的不懈努力,在短短十余年內,已經找到了許多較有希望的新类固醇激素,其中的某一些正广泛地应用或試用于各种疾病的治疗。今将这方面研究的成果綜述于后。本文着重介紹腎上腺皮貭激素的新进展。
Steroids, especially adrenal hormones in the clinical application of a wide range of treatment of many types of diseases, it can be compared with sulfa drugs or antibiotics. However, long-term use of these hormones, often have serious side effects, its clinical application is subject to certain restrictions. Therefore, the search for a powerful and less side effects of new steroids, with great practical and theoretical significance. Due to the unremitting efforts of researchers from all over the world, many promising new steroid hormones have been found in more than ten years, some of which are widely used or tried for the treatment of various diseases. The results of this research are summarized below. This article highlights new advances in adrenal hormones.