恶性肉芽肿是以非特异性、进行性、坏死溃疡为特征的临床综合病征。我科从1976年至1980年,经病理证实并有随访者共7例,结合文献复习如下。临床资料本组7例中,Wegener′s肉芽肿病2例;中线恶性网织细胞增多症(以下简称中线恶网)5例。所有病例于活检证实诊断后进行治疗,显效者进行定期随访,死亡2例作了 Malignant granuloma is a non-specific, progressive, necrotic features of the clinical syndrome. Our department from 1976 to 1980, pathologically confirmed and followed up a total of 7 cases, combined with the literature review below. Clinical data of this group of 7 cases, Wegener’s granulomatosis in 2 cases; median malignant reticuloendothelial disease (hereinafter referred to as the midline evil net) in 5 cases. All cases were diagnosed after biopsy diagnosis and treatment, effective follow-up, were killed in 2 cases