疟疾具有易于复发的特点,特别是间日疟可出现多次反复,因而给防治工作带来不少困难。对疟疾复发机理的正确认识,在灭疟实践上具有重要的指导意义,它有助于灭疟规划的制定以及治疗、预防疟疾的药物的合理应用。关于疟疾复发的原因曾经有过不少解释。自1948年Shortt和Garnham等发现人类疟原虫红细胞外循环后,问题似乎已 Malaria has the characteristics of being easy to relapse. In particular, there may be many repetitions of vivax malaria, which brings many difficulties in prevention and control work. Correct understanding of the mechanism of malaria relapse has an important guiding significance in the practice of malaria control. It is helpful for the formulation of malaria control programs and the rational application of drugs for the treatment and prevention of malaria. There have been many explanations for the reasons for the recurrence of malaria. After Shortt and Garnham et al found human erythrocytic circulation of human Plasmodium in 1948, the problem seemed to have been