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Objective To study the relationship between insulin resistance and blood pressure and blood lipid in patients with type II diabetes mellitus complicated with hypertension.Methods The serum concentration of fasting glucose,insulin,lipids and the level of blood pressure were measured in 56 patients with type II diabetes mellitus complicated with hypertension.Results The insulin sensitivity index(ISI) decreased in patients with type II diabetes mellitus complicated with hypertension compared with the patients with type II diabetes mellitus with normal blood pressure(P< 0.05).A negative correlation with hypertension was found between ISI and SBP,DBP,TG,ApoB in patients with type II diabetes mellitus complicated with hypertension(P<0.05).There was a positive correlation between ISI and HDL in patients with type II diabetes mellitus complicated with hypertension(P<0.05).Conclusion Insulin resistance presents in patients of type II diabetes mellitus complicated with hypertension.Insulin resistance is the major cause of hypertension and lipid metabolic disturbance in patients with type II diabetes mellitus complicated with hypertension.
Objective To study the relationship between insulin resistance and blood pressure and blood lipid in patients with type II diabetes mellitus complicated with hypertension. Methods The serum concentration of fasting glucose, insulin, lipids and the level of blood pressure were measured in 56 patients with type II diabetes mellitus complicated with hypertension. Results of the insulin sensitivity index (ISI) decreased in patients with type II diabetes mellitus complicated with hypertension compared with the patients with type II diabetes mellitus with normal blood pressure (P <0.05). A negative correlation with hypertension was found between ISI and SBP, DBP, TG, ApoB in patients with type II diabetes mellitus complicated with hypertension (P <0.05). There was a positive correlation between ISI and HDL in patients with type II diabetes mellitus complicated with hypertension ) .Conclusion Insulin resistance presents in patients of type II diabetes mellitus complicated with hypertension. Insulin resis tance is the major cause of hypertension and lipid metabolic disturbance in patients with type II diabetes mellitus complicated with hypertension.