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目的:比较泮托拉唑与奥美拉唑治疗消化性溃疡(PU)合并出血的临床效果。方法:选择经纤维胃镜检查确诊为PU出血80例,随机分为2组:奥美拉唑组(甲组)与泮托拉唑组(乙组)。观察两组的疗效和不良反应。结果:治疗(2-10)天后,两组患者的呕血和黑便次数与第1天相比差别有显著性(P<0.05)。两组均无不良反应。结论:泮托拉唑优于奥美拉唑治疗消化道溃疡合并出血,且无不良反应,见效快,出血时间缩短,能快速缩短病程及提高临床治愈率。
Objective: To compare the clinical effects of pantoprazole and omeprazole in the treatment of peptic ulcer (PU) with hemorrhage. Methods: 80 cases diagnosed as PU haemorrhage by fiber endoscopy were randomly divided into 2 groups: omeprazole group (group A) and pantoprazole group (group B). The efficacy and adverse reactions of the two groups were observed. Results: After treatment (2-10) days, there was a significant difference between the two groups in the number of hematemesis and stools compared with the first day (P <0.05). No adverse reactions in both groups. Conclusion: Pantoprazole is better than omeprazole in the treatment of gastrointestinal ulcer combined with hemorrhage, and no adverse reactions, quick, bleeding time shortened, can quickly shorten the course and improve the clinical cure rate.