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目的 应用光学相干断层扫描(OCT)观察年龄相关性黄斑变性的不同特征。方法 116例临床上荧光造影诊断为老年性黄斑变性的病人,160只眼,其中男性67例(88只眼),女性49例(72只眼)。干性者36例(56只眼),其中女性19例(32只眼),男性17例(24只眼),平均年龄为68.5±9.82岁,平均视力为0.58±0.29。湿性者80例(104只眼),其中女性30例(40只眼),男性50例(64只眼),平均年龄为71.8±8.69岁,平均视力为0.253±0.293。所有病例在散瞳下用4mm长扫描线行放射状扫描。结果 中心凹处视网眼厚度干性病变组为168.01±38.24μm,湿性病变组为220.2±114μm;色素1皮厚度干性病变组为128.18±47.24μm。湿性病变组为287±157.2μm。结论 OCT可以帮助观察年龄相关性黄斑变性的发展及新生血管膜的特征及位置,对于指导临床治疗有重大意义。
Objective To observe the different features of age-related macular degeneration by optical coherence tomography (OCT). Methods One hundred and sixty - six eyes of 116 patients with age - related macular degeneration diagnosed by clinical fluorescence imaging were enrolled, including 67 males (88 eyes) and 49 females (72 eyes). Thirty-six cases (56 eyes) had dryness, including 19 females (32 eyes) and 17 males (24 eyes). The mean age was 68.5 ± 9.82 years and the mean visual acuity was 0.58 ± 0.29. There were 80 wet eyes (104 eyes), including 30 females (40 eyes) and 50 males (64 eyes). The mean age was 71.8 ± 8.69 years with an average of 0.253 ± 0.293 eyes. All cases were scanned radially with a 4 mm long scan line under mydriasis. Results The thickness of the retinaculum in the central depression was 168.01 ± 38.24μm in the diseased group and 220.2 ± 114μm in the wet lesion group, and 128.18 ± 47.24μm in the dry lesion group. Wet disease group was 287 ± 157.2μm. Conclusion OCT can help observe the development of age-related macular degeneration and the characteristics and location of neovascular membrane, which is of great significance for guiding the clinical treatment.