溶血、尿毒综合征是由急性微小血管病性溶血性贫血,血小板减少和急性肾功能衰竭所组成,并且在肾小动脉和肾小球毛细血管有纤维蛋白和血小板沉着,伴有整个或部分肾皮质坏死。在血清和尿内有纤维蛋白降解物,提示血管内血栓可能发生一些溶解。由于本病有这些病理上的特点,肝素曾被广泛应用于治疗,但本病的发病率和死亡率仍较高。在本病的血清和尿内,纤维蛋白降解物的浓度很高,常无周身性纤维蛋白溶解的激活作用。所以,肾小球毛细血管内 Hemolysis, uremic syndrome is caused by acute microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure, and in the renal arterioles and glomerular capillary fibrin and platelet deposition, with all or part of the kidney Cortical necrosis. There are fibrin degradation products in serum and urine, suggesting some dissolution of intravascular thrombosis may occur. As the disease has these pathological features, heparin has been widely used in the treatment, but the incidence and mortality of the disease is still high. Serum and urine in the disease, fibrin degradation of high concentrations, often without systemic fibrinolytic activation. So glomerular capillaries