【摘 要】
：
The estrogen receptor is a target for therapeutic agents for hormone replacement in menopausal women, osteoporosis, reproductive cancers such as breast cancer,
【机 构】
：
Key Laboratory of Structure-Based Drug Design & Discovery,Department of Organic Chemistry
论文部分内容阅读
The estrogen receptor is a target for therapeutic agents for hormone replacement in menopausal women, osteoporosis, reproductive cancers such as breast cancer, uterine cancer and prostate cancer. 1,4-Dihydrothieno [3',2':5,6]thiopyrano [4,3-c]pyrazole-3-carboxylic amide derivatives were designed, synthesized and biological evaluated as potential estrogen receptor antagonists.
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