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4.用补体裂解产物鉴别先兆子痫和活动性SLE(Ordorica SA et al) 为评价孕期系统性红斑狼疮(SLE)的活动,并与先兆子痫鉴别,作者前瞻性地测定了14例SLE孕妇、10例先兆子痫孕妇和11例正常孕妇的补体裂解产物(CSP):Ba、Bb、Sc5b-9和C_4d。14例狼疮病人中5例为突发,2例发生于孕中期,3例发生于晚期。活动与非活动狼疮孕妇各项指标平均值如下:Ba1.6对0.6,P<0.01,Bb 1.1对0.3,P<0.02,S_((?)5b)-9,1.7对0.5,P<0.01;C_411对21无显著性,C_398对123无显著性,CH5085对179,(P<0.01)。10例先兆子痫孕妇中3例Ba水平升高,可是她们的CH50均在或接近正常范围。而在明显不同于5例活动性狼疮孕妇其升高的Ba总是与CH
4. Identification of preeclampsia and active SLE by the use of complement cleavage products (Ordorica SA et al) To assess the activity of systemic lupus erythematosus (SLE) during pregnancy and to identify preeclampsia, prospectively determined 14 pregnant women with SLE , 10 cases of preeclampsia and 11 cases of normal pregnant women’s complement pyrolysis products (CSP): Ba, Bb, Sc5b-9 and C_4d. Five of the 14 patients with lupus were abrupt, two in the second trimester, and three in the late. The average of various indexes of active and inactive lupus pregnant women were as follows: Ba1.6 to 0.6, P <0.01, Bb 1.1 to 0.3, P <0.02, S_ ((?) 5b) -9,1.7 to 0.5, P < C_411 was not significant for 21, C_398 for 123 was not significant, CH5085 for 179, (P <0.01). Three of 10 pregnant women with preeclampsia had elevated levels of Ba, but their CH50 was at or near the normal range. In contrast to the 5 active lupus pregnant women, their elevated Ba was always associated with CH