HELLP综合征(溶血、肝酶升高和血小板减少)是重度妊高征的一种多系统疾病形式,特征为微血管溶血性贫血、肝功异常和血小板减少,重者出现弥漫性血管内凝血(DIC)。发病率占重度妊高征的4％～12％。早期及轻症患者不易发现,需借助实验室检验。目前尚缺乏HELLP综合征自然病程方面的资料,特别是分娩前后各项实验室指标的变化情况。 HELLP syndrome (hemolysis, elevated liver enzymes and thrombocytopenia) is a multi-systemic disease form of severe pregnancy-induced hypertension characterized by microvascular hemolytic anemia, abnormal liver function and thrombocytopenia, severe diffuse intravascular coagulation ( DIC). Incidence of severe pregnancy-induced hypertension rate of 4% to 12%. Early and mild patients are not easy to find, need to rely on laboratory tests. Currently there is a lack of information on the natural history of HELLP syndrome, especially before and after labor changes in various laboratory indicators.