尿酸水平及高尿酸血症的民族差异性研究

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目的:分析尿酸水平及高尿酸血症的民族差异性。方法:采用随机抽样的方法在乌鲁木齐市健康体检人群中选择维吾尔族和汉族作为研究对象,检测其尿酸水平并分析民族之间的差异性。结果:汉族尿酸水平和高尿酸血症检出率均高于维吾尔族,男性尿酸水平和高尿酸血症检出率也高于女性,且发病年龄早于女性。尿酸值和高尿酸血症有随年龄增长而增长的趋势,尤其是女性在50岁以后有明显的增高。结论:新疆汉族和维吾尔族尿酸水平和高尿酸血症的发生存在民族差异性,在两个民族生活方式和饮食习惯逐渐趋向一致的情况下,仍然表现出的民族差异,可能与两个民族的遗传背景有关,因此了解不同民族正常人群的尿酸水平和高尿酸血症发病率对于探讨该疾病的发病机制具有重要的意义。 Objective: To analyze the national differences of uric acid level and hyperuricemia. Methods: Uygur and Han nationality were selected from the health examination population of Urumqi by random sampling method. The levels of uric acid were detected and the differences among different ethnic groups were analyzed. Results: The prevalence of uric acid and hyperuricemia in Han nationality were higher than that of Uyghur nationality. The prevalence of uric acid and hyperuricemia in males was also higher than that in females and the incidence was earlier than that in females. Uric acid levels and hyperuricemia tend to increase with age, especially in women after the age of 50 significantly increased. Conclusion: There are ethnic differences in the level of uric acid and hyperuricemia in Han and Uygur ethnic communities in Xinjiang. The ethnic differences that still exist between the two ethnic groups tend to coincide with their lifestyle and eating habits, which may be related to the differences between the two nationalities Genetic background, so understanding the normal population of different ethnic groups of uric acid levels and the incidence of hyperuricemia for exploring the pathogenesis of the disease is of great significance.
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