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宫颈癌诊断虽然较容易,但有必要改进治疗方法提高病人生存率。在预报疾病的预后上也同样有用。可筛选出其中的高危病人以便加强治疗或密切随访。宫颈癌的预后因素包括瘤的扩展,细胞类型,瘤细胞对淋巴血管的浸润,肿瘤对治疗的反应,肿瘤相关抗原和宿主对肿瘤的应答。本文研究肿瘤抗原TA-4对于预报宫颈癌预后的价值,并以外周血淋巴细胞百分率来估计宿主对癌的防御应答。作者将135例组织学证明为宫颈鳞癌的Ⅱ-Ⅳ期病人分为二组。60例Ⅱ期患者作了根治性子宫切除术和盆腔淋巴结切除术,其余75例以放疗为主,辅以化疗。皆随访2年。治疗前用放射免疫法测定血
Although the diagnosis of cervical cancer is easier, but there is a need to improve the treatment to improve patient survival. It is also useful in predicting the prognosis of a disease. High-risk patients can be screened for enhanced treatment or close follow-up. Prognostic factors of cervical cancer include tumor expansion, cell type, tumor cell infiltration into lymphatic vessels, tumor response to therapy, tumor-associated antigens and host response to tumors. This article studies the value of tumor antigen TA-4 in predicting the prognosis of cervical cancer, and estimates the host’s defensive response to cancer based on the percentage of peripheral blood lymphocytes. The authors classify 135 patients with stage II-IV histological evidence of cervical squamous cell carcinoma into two groups. 60 cases of stage Ⅱ patients underwent radical hysterectomy and pelvic lymph node dissection, and the remaining 75 cases of radiotherapy, supplemented by chemotherapy. All patients were followed up for 2 years. Blood was measured by radioimmunoassay before treatment